THE SMART TRICK OF LINK THR777 THAT NO ONE IS DISCUSSING

The smart Trick of link thr777 That No One is Discussing

The smart Trick of link thr777 That No One is Discussing

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Stars characterize the mixture evaluate status, or the level of overview supporting the combination germline classification for this VCV history.

These citations are determined by LitVar utilizing the rs selection, so They could contain citations for more than one variant at this spot. You should critique the LitVar success carefully for the variant of interest. Record last current May possibly 12, 2024 

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The influence with the variant on RNA or protein purpose, based upon experimental evidence from submitters.

This sequence transform has an effect on codon 777 of your GAA mRNA. It's really a 'silent' improve, this means that it doesn't change the encoded amino acid sequence in the GAA protein. This variant also falls at the last nucleotide of exon sixteen, and that is Component of the consensus splice web-site for this exon. This variant is current in population databases (rs375311693, gnomAD 0.03%). This variant hasn't been described while in the literature in men and women affected with GAA-related disorders.

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